Janus kinase (JAK) inhibitors have had game-changing effects for patients with psoriasis, atopic dermatitis, vitiligo, and alopecia areata, but the use of these potent medications has been associated with JAK inhibitor-associated acne (JAKne). In a systematic review and meta-analysis of 25 clinical trials comprising 10,839 participants, people taking JAK inhibitors were close to four times more likely to develop acne than their counterparts taking placebo. This association was stronger among studies conducted among patients with dermatologic indications.The study is published in JAMA Dermatology. TDD reached out to experts to learn more about JAKne and how to treat it. Click here to know more.
